Description

Pyrrole-2,3,4,5-D4 is a deuterated isotopologue of pyrrole, where four hydrogen atoms are replaced with deuterium, a stable hydrogen isotope. This deuteration is critical for applications requiring reduced signal interference in spectroscopic analysis and enhanced metabolic stability in research. It is primarily utilized by analytical chemists, pharmaceutical researchers, and material scientists working in nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and drug metabolism studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis due to its nearly identical chemical properties with distinct mass.
• NMR Spectroscopy Solvent & Reagent: Employed as a deuterated solvent or a labeled reagent to simplify NMR spectra and study reaction mechanisms without proton signal interference.
• Pharmaceutical Research & Drug Development: Serves as a stable isotope-labeled tracer in pharmacokinetic, metabolic stability, and absorption, distribution, metabolism, and excretion (ADME) studies.
• Organic Synthesis & Catalysis Research: Acts as a building block or probe in synthesizing deuterated compounds and investigating catalytic processes using deuterium kinetic isotope effects (DKIE).
• Material Science: Used in the development of organic electronic materials and conductive polymers where isotopic labeling helps study structure-property relationships.

Basic Information

Product Name	Pyrrole-2,3,4,5-D4
CAS No.	17767-94-1
Molecular Formula	C4D4NH
Molecular Weight	71.11 g/mol
Synonyms	Perdeuterated Pyrrole (d4); Pyrrole-d4; [2,3,4,5-2H4]Pyrrole; 1H-Pyrrole-2,3,4,5-d4; Deuterated Pyrrole; Pyrrole (D4); Tetradeuteropyrrole; Azole-d4
EINECS	Contact for details

Quality Control

Every batch of Pyrrole-2,3,4,5-D4 is produced and analyzed under strict quality management protocols. We ensure high chemical and isotopic purity through advanced analytical techniques, including NMR, MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profiles is provided with each shipment to guarantee consistency for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Isotopic Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.