Description

Pyrimidine, 2,5-Difluoro- (8Ci,9Ci) is a high-purity fluorinated pyrimidine derivative, a key building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel materials. Its specific substitution pattern makes it a critical scaffold for medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially in antiviral and anticancer drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms for enhanced bioactivity and stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and electronic materials due to its aromatic heterocyclic structure.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag in biochemical research to study enzyme mechanisms and protein interactions.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a core component or dopant in the synthesis of novel electroluminescent materials.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Item	Detail
Product Name	Pyrimidine, 2,5-Difluoro- (8Ci,9Ci)
CAS No.	17573-84-1
Molecular Formula	C4H2F2N2
Molecular Weight	116.07 g/mol
Synonyms	2,5-Difluoropyrimidine; 2,5-Difluoro-1,3-diazine; 2,5-Difluoropyrimidine; 2,5-Difluoro-1,3-diazabenzene; Pyrimidine, 2,5-difluoro-; 2,5-Difluoropyrimidine (8CI,9CI); 2,5-Difluoro-pyrimidine; 2,5-Difluoro-1,3-diazine
EINECS	Contact for details

Quality Control

Every batch of 2,5-Difluoropyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality commitment supports applications requiring regulatory compliance, including those under ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.