Description

5-Bromo-1,3-Dichloro-2-Fluorobenzene is a high-purity halogenated benzene derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its halogenated structure contributes to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated and halogenated aromatic cores essential in electronic materials for displays and lighting.
• Polymer Chemistry: Acts as a monomer or modifier in the synthesis of high-performance polymers, including polyarylates and engineering plastics, to enhance thermal and chemical resistance.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, enabling rapid diversification of chemical libraries.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating complex molecular architectures.

Basic Information

Product Name	5-Bromo-1,3-Dichloro-2-Fluorobenzene
CAS No.	17318-08-0
Molecular Formula	C6H2BrCl2F
Molecular Weight	243.89 g/mol
Synonyms	1-Bromo-3,5-Dichloro-2-Fluorobenzene; 2-Fluoro-1,3-Dichloro-5-Bromobenzene; 3,5-Dichloro-2-Fluorobromobenzene; 5-Bromo-2-Fluoro-1,3-Dichlorobenzene; 2-Fluoro-3,5-Dichlorobromobenzene; Benzene, 5-bromo-1,3-dichloro-2-fluoro-; 17318-08-0
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,3-Dichloro-2-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.