Description

3-Fluorophenylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, essential for forming new carbon-carbon bonds in complex organic synthesis. Its value lies in its ability to introduce the versatile 3-fluorophenyl moiety into target molecules, a key step in creating compounds with modified electronic and steric properties. This product is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for creating fluorinated active pharmaceutical ingredients (APIs) and drug candidates, where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that benefit from the specific properties of the fluorophenyl group.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the creation of fluorinated monomers, polymers, and liquid crystals for advanced electronic and optical applications.
• Fine Chemical and Flavor/Fragrance Synthesis: Facilitates the production of complex, fluorinated aromatic compounds used in specialty chemicals.
• Academic and R&D Laboratories: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Item	Details
Product Name	3-Fluorophenylmagnesium Bromide
CAS No.	17318-03-5
Molecular Formula	C6H4FMgBr
Molecular Weight	199.30 g/mol
Synonyms	(3-Fluorophenyl)magnesium bromide; m-Fluorophenylmagnesium bromide; 1-Fluoro-3-(bromomagnesio)benzene; Magnesium, bromo(3-fluorophenyl)-; Grignard reagent 3-FC6H4MgBr
EINECS	Contact for details

Quality Control

Our 3-Fluorophenylmagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is assured through rigorous analytical testing, including titration to determine concentration and purity. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile, easily oxidized, and reacts violently with protic solvents. It must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, well-ventilated area, away from heat, moisture, and incompatible materials. Typical storage temperature is 2-8°C for extended stability, though specific recommendations depend on the solvent and concentration.

Specification

Item	Specification
Appearance	Clear to slightly colored solution
Concentration (in specified solvent)	0.5 M - 2.0 M (Typical in THF or Diethyl Ether)
Assay (by Titration)	≥ 95% (as Grignard reagent)
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.