Description

5-Chlorosulfonyl-2-Hydroxybenzoic Acid is a versatile and reactive aromatic sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive sulfonyl chloride group and a carboxylic acid moiety, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including diuretics, carbonic anhydrase inhibitors, and anti-glaucoma agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require the sulfonylurea or sulfonamide pharmacophore.
• Dyestuff and Pigment Manufacturing: Acts as an intermediate for creating sulfonated azo dyes and high-performance pigments, enhancing color fastness and solubility.
• Polymer Modification: Employed to introduce sulfonyl chloride functional groups into polymer chains for subsequent cross-linking or to impart specific ionic characteristics.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new reaction pathways and creating novel chemical entities.
• Ligand and Chelating Agent Synthesis: Serves as a starting material for designing complexing agents used in metal extraction and catalysis.

Basic Information

Product Name	5-Chlorosulfonyl-2-Hydroxybenzoic Acid
CAS No.	17243-13-9
Molecular Formula	C7H5ClO5S
Molecular Weight	236.63 g/mol
Synonyms	5-(Chlorosulfonyl)salicylic acid; 2-Hydroxy-5-chlorosulfonylbenzoic acid; 5-Chlorosulfonylsalicylic Acid; Benzoic acid, 5-(chlorosulfonyl)-2-hydroxy-; 5-Sulfonyl Chloride Salicylic Acid; 5-Chlorosulfonyl-2-hydroxybenzoic acid; 5-Carboxy-2-hydroxyphenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Chlorosulfonyl-2-Hydroxybenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed to exclude moisture. Store away from incompatible materials such as bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.