Description

1-(Chlorodifluoromethyl)-2-Fluorobenzene is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both chlorodifluoromethyl and fluorine substituents, makes it a valuable precursor for introducing difluoromethyl and related motifs into complex molecules. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of bioactive molecules, particularly those requiring difluoromethyl ether or difluoromethylaryl groups.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides where fluorination enhances stability and activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials due to its ability to modify electronic properties and intermolecular interactions.
• Fluorinated Polymer Modification: Employed to introduce fluorinated side chains or cross-linking agents into specialty polymers to alter surface properties and chemical resistance.
• Organic Synthesis Reagent: Acts as an electrophile in cross-coupling reactions or as a source of the -CF2Cl group in nucleophilic substitution reactions under controlled conditions.

Basic Information

Product Name	1-(Chlorodifluoromethyl)-2-Fluorobenzene
CAS No.	17054-13-6
Molecular Formula	C7H4ClF3
Molecular Weight	180.55 g/mol
Synonyms	2-Fluorobenzyl Chloride, α,α-Difluoro; 2-Fluoro-α,α-difluorobenzyl Chloride; 1-(Chlorodifluoromethyl)-2-fluorobenzene; o-Fluorobenzal Chloride, Difluoro; (2-Fluorophenyl)difluoromethyl Chloride; Benzene, 1-(chlorodifluoromethyl)-2-fluoro-; α-Chloro-2-fluoro-α,α-difluorotoluene
EINECS	Contact for details

Quality Control

Our production of 1-(Chlorodifluoromethyl)-2-Fluorobenzene adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is characterized by GC, NMR, and other appropriate analytical techniques to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent and highly volatile compound, it is recommended to store at controlled room temperature (15-25°C) and keep containers tightly sealed when not in use to prevent evaporation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.