Description

5,8-Difluoroquinoline is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique fluorine substitution pattern enables precise modulation of biological activity and physicochemical properties. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, material science, and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated quinolone antibiotics and other therapeutic agents.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging fluorine's ability to enhance metabolic stability and bioavailability.
• Material Science: Building block for creating organic electronic materials, such as ligands for OLEDs and other fluorophore-based systems.
• Chemical Synthesis: Versatile scaffold for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.

Basic Information

Product Name	5,8-Difluoroquinoline
CAS No.	16650-32-1
Molecular Formula	C9H5F2N
Molecular Weight	165.14 g/mol
Synonyms	5,8-Difluoroquinoline; Quinoline, 5,8-difluoro-; 16650-32-1; 5,8-Difluorochinolin; 5,8-Difluoro-chinolin; 5,8-Difluoro-1-azanaphthalene
EINECS	Contact for details

Quality Control

Our 5,8-Difluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards for production, ensuring consistency and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.