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2-Chloro-6-(Trifluoromethyl)Phenyl CAS NO 16583-76-9
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CAS No.:16583-76-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Chloro-6-(Trifluoromethyl)Phenyl is a versatile halogenated aromatic building block, distinguished by its unique combination of chlorine and trifluoromethyl substituents. This compound is highly valued for its role as a critical intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where it imparts desirable biological activity and metabolic stability. It is essential for R&D chemists and production specialists in the fine chemical, crop protection, and active pharmaceutical ingredient (API) manufacturing sectors seeking to develop novel compounds with enhanced properties.
Application
- Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
- Pharmaceutical Building Block: Used in medicinal chemistry for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system and inflammatory diseases.
- Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
- Material Science Research: Employed in the development of advanced polymers and liquid crystals where specific aromatic units are required.
- Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring new chemical entities and reaction pathways.
Basic Information
| Product Name | 2-Chloro-6-(Trifluoromethyl)Phenyl |
| CAS No. | 16583-76-9 |
| Molecular Formula | C7H4ClF3 |
| Molecular Weight | 180.55 g/mol |
| Synonyms | 1-Chloro-2-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluorotoluene; 2-Chlorobenzotrifluoride; o-Chlorobenzotrifluoride; 2-Chloro-α,α,α-trifluoromethylbenzene; (2-Chloro-6-trifluoromethyl)benzene; 2-Chloro-6-trifluoromethyl benzene; 2-Chloro-α,α,α-trifluoro toluene |
| EINECS | Contact for details |
Quality Control
Our 2-Chloro-6-(Trifluoromethyl)Phenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to guarantee traceability and batch-to-batch consistency for your production processes.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-25°C. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Purity (GC/HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Density (20°C) | ~1.38 g/cm³ |
| Boiling Point | ~155-160°C |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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