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2-Chloro-6-(Trifluoromethyl)Phenyl CAS NO 16583-76-9


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CAS No.:16583-76-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Chloro-6-(Trifluoromethyl)Phenyl is a versatile halogenated aromatic building block, distinguished by its unique combination of chlorine and trifluoromethyl substituents. This compound is highly valued for its role as a critical intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where it imparts desirable biological activity and metabolic stability. It is essential for R&D chemists and production specialists in the fine chemical, crop protection, and active pharmaceutical ingredient (API) manufacturing sectors seeking to develop novel compounds with enhanced properties.

Application

  • Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
  • Pharmaceutical Building Block: Used in medicinal chemistry for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system and inflammatory diseases.
  • Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
  • Material Science Research: Employed in the development of advanced polymers and liquid crystals where specific aromatic units are required.
  • Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories exploring new chemical entities and reaction pathways.

Basic Information

Product Name 2-Chloro-6-(Trifluoromethyl)Phenyl
CAS No. 16583-76-9
Molecular Formula C7H4ClF3
Molecular Weight 180.55 g/mol
Synonyms 1-Chloro-2-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluorotoluene; 2-Chlorobenzotrifluoride; o-Chlorobenzotrifluoride; 2-Chloro-α,α,α-trifluoromethylbenzene; (2-Chloro-6-trifluoromethyl)benzene; 2-Chloro-6-trifluoromethyl benzene; 2-Chloro-α,α,α-trifluoro toluene
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Quality Control

Our 2-Chloro-6-(Trifluoromethyl)Phenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to guarantee traceability and batch-to-batch consistency for your production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-25°C. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC/HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Density (20°C) ~1.38 g/cm³
Boiling Point ~155-160°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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