Description

7-(Trifluoromethyl)Quinazolin-4(3H)-One is a high-value, fluorinated quinazolinone derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl group, enabling the development of novel compounds with enhanced metabolic stability and bioavailability. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the CF3 group can improve efficacy and environmental profile.
• Material Science: Serves as a precursor for advanced organic electronic materials and fluorinated polymers.
• Chemical Synthesis: A versatile scaffold in medicinal and combinatorial chemistry for creating diverse heterocyclic libraries.
• Academic & R&D: Employed in universities and contract research organizations (CROs) for fundamental studies in fluorine chemistry and heterocycle synthesis.

Basic Information

Product Name	7-(Trifluoromethyl)Quinazolin-4(3H)-One
CAS No.	16499-58-4
Molecular Formula	C9H5F3N2O
Molecular Weight	214.15 g/mol
Synonyms	4(3H)-Quinazolinone, 7-(trifluoromethyl)-; 7-(Trifluoromethyl)-4(3H)-quinazolinone; 7-Trifluoromethylquinazolin-4(3H)-one; 7-Trifluoromethyl-4-hydroxyquinazoline; 7-CF3-Quinazolin-4(3H)-one; 7-Trifluoromethyl-3,4-dihydroquinazolin-4-one; 16499-58-4
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)Quinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids/bases and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.