Description

Quinazoline, 6-Fluoro- (8Ci) is a fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to synthesize potential drug candidates, agrochemicals, and other specialty chemicals where the quinazoline scaffold is desired.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of potential kinase inhibitors, anticancer agents, and other bioactive molecules featuring the quinazoline core.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the fluorine atom can enhance biological activity and stability.
• Material Science: Employed in the research of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology: Utilized as a probe or tag in biochemical research to study enzyme mechanisms or protein interactions.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new fluorination reactions or heterocyclic chemistry.

Basic Information

Product Name	Quinazoline, 6-Fluoro- (8Ci)
CAS No.	16499-44-8
Molecular Formula	C8H5FN2
Molecular Weight	148.14 g/mol
Synonyms	6-Fluoroquinazoline; Quinazoline, 6-fluoro-; 6-Fluoro-1,3-diazanaphthalene; 6-Fluoro-benzo[d]pyrimidine; Fluorquinazoline; 6-F-Quinazoline; 16499-44-8 (CAS)
EINECS	Contact for details

Quality Control

Our Quinazoline, 6-Fluoro- (8Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.