Description

3H-Diazirine-3,3-Dipropanoic Acid is a versatile heterocyclic carboxylic acid derivative featuring a highly reactive diazirine ring. This compound is valued for its ability to act as a photoactivatable crosslinking agent, enabling the study of biomolecular interactions and the development of advanced materials. It is primarily sought by researchers and manufacturers in the pharmaceutical, bioconjugation, and polymer science industries for applications requiring precise, light-induced covalent bonding.

Application

• Photoaffinity Labeling (PAL): A critical tool in chemical biology and drug discovery for mapping binding sites and identifying molecular targets of bioactive compounds.
• Bioconjugation & Probe Synthesis: Used to create photo-crosslinkable probes, antibodies, and other biomolecular conjugates for diagnostic and therapeutic research.
• Polymer & Material Science: Serves as a crosslinker or functional monomer for synthesizing light-responsive polymers, hydrogels, and surface coatings.
• Proteomics & Structural Biology: Facilitates the capture and analysis of transient protein-protein or protein-ligand interactions.
• Chemical Biology Research: Enables the study of metabolic pathways and enzyme mechanisms through in-situ crosslinking strategies.

Basic Information

Product Name	3H-Diazirine-3,3-Dipropanoic Acid
CAS No.	16297-98-6
Molecular Formula	C7H10N2O4
Molecular Weight	186.17 g/mol
Synonyms	3,3-Dipropanoic Acid Diaziridine; 3-(3H-Diazirin-3-yl)propanoic Acid; Diazirine-3,3-dipropionic Acid; 3-[3-(Carboxymethyl)-3H-diazirin-3-yl]propanoic Acid; 3,3'-(3H-Diazirine-3,3-diyl)dipropanoic Acid; Photoactivatable Crosslinker; Diazirine Crosslinker
EINECS	Contact for details

Quality Control

Our 3H-Diazirine-3,3-Dipropanoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and prolong shelf life. Allow the container to reach room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.