Description

4-Iodo-2,3,5,6-Tetrafluoropyridine is a highly fluorinated pyridine derivative, serving as a versatile and valuable halogenated building block in advanced organic synthesis. Its unique structure, combining iodine and fluorine substituents, makes it a critical intermediate for introducing specific functional groups into complex molecules. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a building block for creating novel fluorinated ligands used in transition metal catalysis and cross-coupling reactions.
• Materials Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials to modify solubility, thermal stability, and dielectric properties.
• Radiochemistry: The iodine-127 isotope in the molecule provides a stable analog for developing radiolabeled (e.g., Iodine-125 or Iodine-131) tracers for imaging and diagnostic applications.
• Chemical Library Development: A valuable scaffold for constructing diverse compound libraries in high-throughput screening and medicinal chemistry programs.

Basic Information

Product Name	4-Iodo-2,3,5,6-Tetrafluoropyridine
CAS No.	16297-19-1
Molecular Formula	C5F4IN
Molecular Weight	296.96 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-iodopyridine; 4-Iodotetrafluoropyridine; Tetrafluoro-4-iodopyridine; Pyridine, 4-iodo-2,3,5,6-tetrafluoro-; Iodotetrafluoropyridine
EINECS	Contact for details

Quality Control

Our 4-Iodo-2,3,5,6-Tetrafluoropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.