Description

2,3,5,6-Tetrafluoro-4-methylpyridine is a highly fluorinated pyridine derivative, a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring a perfluorinated ring system, makes it a critical intermediate for introducing fluorine atoms into complex molecules, thereby modifying their electronic properties, metabolic stability, and lipophilicity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise fluorination to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in the creation of fluorine-containing drugs to enhance bioavailability and metabolic resistance.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-based components in electronic display technologies and organic light-emitting diodes (OLEDs), improving charge transport and device stability.
• Polymer & Material Science: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Catalyst & Ligand Development: Utilized in the synthesis of novel fluorinated ligands for catalysis, enabling new reaction pathways in fine chemical manufacturing.
• Research & Development: A valuable tool for academic and industrial R&D in exploring new fluorination methodologies and the structure-activity relationships of fluorinated compounds.

Basic Information

Item	Details
Product Name	2,3,5,6-Tetrafluoro-4-methylpyridine
CAS No.	16297-14-6
Molecular Formula	C6H3F4N
Molecular Weight	165.09 g/mol
Synonyms	4-Methyl-2,3,5,6-tetrafluoropyridine; 2,3,5,6-Tetrafluoro-4-picoline; Tetrafluoro-4-methylpyridine; 4-Methyltetrafluoropyridine; Perfluoro-4-methylpyridine (common name); 16297-14-6; NSC 406925
EINECS	Contact for details

Quality Control

Every batch of 2,3,5,6-Tetrafluoro-4-methylpyridine is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards through rigorous analytical controls, including chromatography and spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and meet the exacting requirements of our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.