Description

2,3,5,6-Tetrafluoropyridine-4-Carboxaldehyde is a highly fluorinated pyridine derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring an aldehyde group on a perfluorinated pyridine ring, makes it a critical intermediate for introducing fluorinated motifs into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise fluorination to modulate the properties of their products.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of fluorinated drug candidates where the fluorine atoms can enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorinated pyridine core contributes to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized fluorinated ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of advanced materials, such as liquid crystals, organic semiconductors, and polymers, where fluorination tailors electronic properties and stability.
• Custom Synthesis and R&D: A fundamental reagent for medicinal chemistry and process research in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	2,3,5,6-Tetrafluoropyridine-4-Carboxaldehyde
CAS No.	16297-09-9
Molecular Formula	C6HF4NO
Molecular Weight	191.07 g/mol
Synonyms	Perfluoropyridine-4-carboxaldehyde; 4-Formyl-2,3,5,6-tetrafluoropyridine; 2,3,5,6-Tetrafluoro-4-pyridinecarboxaldehyde; Tetrafluoropyridine-4-carbaldehyde; 4-Pyridinecarboxaldehyde, 2,3,5,6-tetrafluoro-; 4-Aldehydotetrafluoropyridine
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrafluoropyridine-4-Carboxaldehyde is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality systems support development and commercial needs, from research quantities to bulk scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.