Description

L-Methionine Sulfoximine is a potent and specific inhibitor of glutamine synthetase, a critical enzyme in nitrogen metabolism. This compound is essential for researchers investigating cellular metabolism, neurological pathways, and plant biochemistry. It is primarily utilized in life science research, pharmaceutical development, and as a biochemical tool for metabolic studies.

Application

• Biochemical Research: A key tool for studying glutamine metabolism, ammonia detoxification, and nitrogen cycling in cell cultures and model organisms.
• Neuroscience Studies: Used to induce experimental models relevant to neurological conditions by inhibiting glutamine synthesis in astrocytes.
• Plant Physiology Research: Applied to investigate the role of glutamine synthetase in plant nitrogen assimilation and amino acid metabolism.
• Pharmaceutical Screening: Serves as a reference compound in drug discovery programs targeting metabolic enzymes and pathways.
• Cell Culture & Metabolism: Employed to modulate intracellular glutamine levels and study its effects on cell proliferation, signaling, and apoptosis.

Basic Information

Product Name	L-Methionine Sulfoximine
CAS No.	15985-39-4
Molecular Formula	C5H12N2O3S
Molecular Weight	180.23 g/mol
Synonyms	L-Methionine-S-sulfoximine; Methionine Sulfoximine; L-MSO; (2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic acid; L-Methionine Sulfoximine; Glutamine Synthetase Inhibitor; NSC 113689; L-Methionine S-Sulfoximine
EINECS	240-138-3

Quality Control

Our L-Methionine Sulfoximine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.