Description

2-Chloro-3-Nitrobenzene-1-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a sulfonyl chloride and a nitro-chloro substituted aromatic ring, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including novel enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and pesticides by introducing the sulfonyl moiety into active molecules.
• Dyestuff and Pigment Manufacturing: Serves as a building block for producing sulfonated azo dyes and other high-performance colorants.
• Polymer Chemistry: Employed as a monomer or cross-linking agent to introduce sulfone groups into polymer backbones, enhancing thermal and chemical resistance.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process development in custom synthesis and scale-up projects.
• Ligand and Catalyst Design: Useful for synthesizing specialized ligands for metal catalysis or functional materials.

Basic Information

Product Name	2-Chloro-3-Nitrobenzene-1-Sulfonyl Chloride
CAS No.	15945-25-2
Molecular Formula	C6H3Cl2NO4S
Molecular Weight	280.06 g/mol
Synonyms	2-Chloro-3-nitrobenzenesulfonyl chloride; 3-Nitro-2-chlorobenzenesulfonyl chloride; 1-Chloro-2-nitro-6-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 2-chloro-3-nitro-; NSC 403119
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-3-Nitrobenzene-1-Sulfonyl Chloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent hydrolysis. Keep away from strong bases, amines, alcohols, and moisture.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.