Description

Trifluoromethanesulfonyl Bromide is a highly reactive triflyl halide used as a versatile reagent for introducing the trifluoromethanesulfonyl group. This compound is valued for its role as a key building block in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is essential for chemists in fine chemical, pharmaceutical, and advanced material sectors seeking to perform bromination or create sulfonamide and sulfonate esters under controlled conditions.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing sulfonamide-based drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require the trifluoromethanesulfonyl moiety for enhanced activity.
• Polymer & Material Science: Serves as a monomer or modifying agent for creating specialty polymers with unique surface properties and chemical resistance.
• Organic Synthesis Reagent: Employed in laboratories for electrophilic bromination reactions and as a precursor to other trifluoromethanesulfonyl derivatives.
• Ligand & Catalyst Preparation: Utilized in the development of novel ligands and organometallic catalysts for asymmetric synthesis.
• Fluorochemical Production: Acts as a key intermediate in the manufacturing of various fluorinated compounds and surfactants.

Basic Information

Product Name	Trifluoromethanesulfonyl Bromide
CAS No.	15458-53-4
Molecular Formula	CBrF3O2S
Molecular Weight	212.98 g/mol
Synonyms	Triflyl Bromide; Bromo(trifluoromethyl)sulfone; Trifluoromethanesulfonic Acid Bromide; Perfluoromethanesulfonyl Bromide; Trifluoromethylsulfonyl Bromide; TfBr; CF3SO2Br; α,α,α-Trifluoromethanesulfonyl Bromide
EINECS	Contact for details

Quality Control

Our Trifluoromethanesulfonyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C. Due to its nature as a strong acid/organic solvent and highly volatile compound, keep away from heat, sparks, and open flame. Store separately from bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~2.0 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.