Description

2-[[(3Alpha,5Beta)-24-Oxo-3-(Sulfooxy)Cholan-24-Yl]Amino]-Ethanesulfonic Acid is a high-purity, functionalized bile acid derivative, specifically designed for advanced research and pharmaceutical development. This compound is valued for its role as a key intermediate in synthesizing novel therapeutic agents and diagnostic probes targeting metabolic and liver-related pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require precise, high-quality building blocks for drug discovery and development.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel bile acid analogs and steroidal drugs targeting liver and metabolic diseases.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to bile acid metabolism and transport proteins.
• Diagnostic Agent Development: Serves as a precursor for developing contrast agents or probes for medical imaging, particularly for hepatobiliary system diagnostics.
• Conjugation Chemistry: The sulfonic acid and amino groups provide handles for conjugation with peptides, proteins, or other molecules to create targeted drug delivery systems.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	2-[[(3Alpha,5Beta)-24-Oxo-3-(Sulfooxy)Cholan-24-Yl]Amino]-Ethanesulfonic Acid
CAS No.	15324-65-9
Molecular Formula	C₂₆H₄₃NO₈S₂
Molecular Weight	561.75 g/mol
Synonyms	3-Sulfoglycocholic Acid; Tauro-3-sulfoglycocholic Acid; 3-Sulfooxy-N-(2-sulfoethyl)cholamide; 3α-Sulfoglycocholic Acid; 3α-Sulfooxyglycocholic Acid; 2-[[(3α,5β)-24-Oxo-3-(sulfooxy)cholan-24-yl]amino]ethanesulfonic Acid; Glycocholic Acid 3-Sulfate; N-(2-Sulfoethyl)-3-sulfooxy-5β-cholan-24-amide
EINECS	Contact for details

Quality Control

Our 2-[[(3Alpha,5Beta)-24-Oxo-3-(Sulfooxy)Cholan-24-Yl]Amino]-Ethanesulfonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and specific tests for residual solvents and moisture to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.