Description

n-Ethyl-β-Methoxy-3-(Trifluoromethyl)Phenethylamine is a specialized fluorinated amine building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a trifluoromethyl group and a methoxy-substituted phenethylamine core, makes it a valuable precursor for creating compounds with tailored electronic and steric properties. This intermediate is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) targets, where the trifluoromethyl group can enhance metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine atoms contribute to improved biological activity and environmental persistence profiles.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis, leveraging the amine functionality for metal coordination or activation.
• Material Science Research: Employed in the synthesis of specialty monomers or additives for advanced polymers, where the fluorinated aromatic system can impart unique surface properties or refractive indices.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function or receptor interactions in biochemical assays.

Basic Information

Product Name	n-Ethyl-β-Methoxy-3-(Trifluoromethyl)Phenethylamine
CAS No.	15235-27-5
Molecular Formula	C₁₂H₁₆F₃NO
Molecular Weight	247.26 g/mol
Synonyms	1-[2-Methoxy-4-(trifluoromethyl)phenyl]-2-ethylaminoethane; 2-Ethylamino-1-[2-methoxy-4-(trifluoromethyl)phenyl]ethane; N-Ethyl-2-methoxy-4-(trifluoromethyl)phenethylamine; β-Methoxy-3-(trifluoromethyl)phenethylamine, N-ethyl-; 15235-27-5; 4-(Trifluoromethyl)-2-methoxyphenethylamine, N-ethyl-
EINECS	Contact for details

Quality Control

Our n-Ethyl-β-Methoxy-3-(Trifluoromethyl)Phenethylamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP requirements for pharmaceutical development, and we can accommodate custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.