Description

2-Chloro-5-Fluoro-1,3-Dimethylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the chloro-fluoro-dimethylbenzene moiety imparts specific biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and liquid crystals with unique electronic or optical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functionalized aromatic rings.
• Dye and Pigment Intermediate: Acts as a precursor in the manufacture of complex dyes and organic pigments.

Basic Information

Product Name	2-Chloro-5-Fluoro-1,3-Dimethylbenzene
CAS No.	14994-16-2
Molecular Formula	C8H8ClF
Molecular Weight	158.60 g/mol
Synonyms	1-Chloro-4-fluoro-2,6-dimethylbenzene; 2,6-Dimethyl-4-fluorochlorobenzene; 4-Fluoro-2,6-dimethylchlorobenzene; 2-Chloro-5-fluoro-1,3-xylene; 5-Fluoro-2-chloro-1,3-dimethylbenzene; 2,6-Dimethyl-1-chloro-4-fluorobenzene; Benzene, 2-chloro-5-fluoro-1,3-dimethyl-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-1,3-Dimethylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical properties is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.18 g/cm³
Boiling Point	~195-200°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.