Description

Roridin A is a potent macrocyclic trichothecene mycotoxin produced by various fungal species, including *Stachybotrys* and *Myrothecium*. This compound is of significant interest in biochemical and pharmacological research due to its powerful inhibitory effects on eukaryotic protein synthesis. It serves as a critical reference standard and research tool for scientists and quality control laboratories in the fields of toxicology, mycology, and environmental safety.

Application

• Analytical Reference Standard: Primary use as a certified high-purity standard for the accurate quantification and identification of trichothecene mycotoxins in food, feed, and environmental samples via HPLC, LC-MS/MS, and ELISA methods.
• Toxicological Research: Essential for studying the mechanisms of cytotoxicity, apoptosis, and immunosuppression induced by trichothecene mycotoxins in cell culture and animal models.
• Mycotoxin Contamination Studies: Used in method development and validation for monitoring mold contamination in agricultural products, building materials, and indoor air quality assessments.
• Biochemical Probe: Employed as a specific inhibitor of protein synthesis to investigate ribosomal function and cellular stress response pathways in eukaryotic systems.
• Pharmaceutical Research: Investigated for its potential in targeted therapies, leveraging its cytotoxic properties in experimental oncology and immunology studies.
• Quality Control & Assurance: Critical for calibrating laboratory equipment and ensuring the accuracy of test kits used in commercial and regulatory testing for mycotoxin presence.

Basic Information

Product Name	Roridin A
CAS No.	14729-29-4
Molecular Formula	C29H40O9
Molecular Weight	532.62 g/mol
Synonyms	Roridin A; Verrucarin A; Antibiotic LL-S88β; 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol, 4,15-diacetate 8-(3-methyl-2-butenoate); LL-S 88β; LL-S88β; NSC 167078; (3α,4β,8α)-4,15-Bis(acetyloxy)-12,13-epoxytrichothec-9-en-3,8-diol 8-(3-methyl-2-butenoate)
EINECS	Contact for details

Quality Control

Our Roridin A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.