Description

5-Fluoro-2-Iodo-1,3-Dimethylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of fluorine and iodine atoms on the benzene ring, which allows for selective functionalization and the construction of complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as drug discovery, material science, and the synthesis of specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated and iodinated aromatic cores for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine atom can improve lipophilicity and environmental persistence.
• Material Science Research: Serves as a monomer or building block for creating advanced organic materials, including liquid crystals, organic semiconductors, and polymers with specific electronic properties.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) to form biaryl and other complex structures.
• Fluorine Chemistry Studies: Employed in methodological research to study the directing effects of fluorine in electrophilic aromatic substitution and other fundamental organic transformations.
• Labeling and Tracer Compounds: Potential use in the synthesis of compounds containing radioactive iodine-125 for diagnostic and research purposes.

Basic Information

Product Name	5-Fluoro-2-Iodo-1,3-Dimethylbenzene
CAS No.	14659-59-7
Molecular Formula	C8H8FI
Molecular Weight	250.05 g/mol
Synonyms	1-Fluoro-3,5-dimethyl-2-iodobenzene; 2-Iodo-5-fluoro-1,3-dimethylbenzene; 3,5-Dimethyl-2-iodofluorobenzene; 5-Fluoro-1,3-dimethyl-2-iodobenzene; 5-Fluoro-2-iodo-m-xylene; m-Xylene, 5-fluoro-2-iodo-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Iodo-1,3-Dimethylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical properties are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.