Description

Zinc Mesoporphyrin is a synthetic metalloporphyrin complex where zinc is chelated within a mesoporphyrin IX framework. This compound is a potent and selective inhibitor of heme oxygenase, a critical enzyme in the heme degradation pathway. It serves as a valuable biochemical tool for research in cellular stress response, oxidative metabolism, and inflammation studies. Key industries requiring this high-purity reagent include pharmaceutical R&D, academic biochemistry laboratories, and diagnostic kit manufacturers.

Application

• Biochemical Research: As a specific inhibitor of heme oxygenase (HO) isoforms (HO-1 and HO-2) to study heme metabolism, oxidative stress, and cytoprotective mechanisms in cell culture and animal models.
• Pharmaceutical Development: Used in preclinical studies to investigate therapeutic pathways related to ischemia-reperfusion injury, neurodegenerative diseases, and inflammatory conditions.
• Diagnostic Reagent Component: Potential use as a reference standard or active component in enzymatic assay kits designed to measure heme oxygenase activity or screen for modulators.
• Photodynamic Therapy (PDT) Research: Exploration of its photosensitizing properties for potential applications in cancer treatment and antimicrobial therapies due to its porphyrin structure.
• Catalysis Studies: Serves as a model compound for mimicking the active sites of metalloenzymes in studies of catalytic mechanisms and biomimetic chemistry.

Basic Information

Product Name	Zinc Mesoporphyrin
CAS No.	14354-67-7
Molecular Formula	C34H36N4O4Zn
Molecular Weight	630.05 g/mol
Synonyms	Zinc Mesoporphyrin IX; ZnMP; Zn-Mesoporphyrin; Mesoporphyrin IX zinc salt; Heme Oxygenase Inhibitor, Zinc Mesoporphyrin; Protoporphyrin IX, 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(2-)-N21,N22,N23,N24 zinc; 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, zinc complex
EINECS	Contact for details

Quality Control

Our Zinc Mesoporphyrin is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and elemental analysis. A detailed Certificate of Analysis (COA) is provided with each batch, documenting purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles to guarantee reliability for your critical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage under inert atmosphere (e.g., argon or nitrogen) at -20°C. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Dark red to purple crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Zinc Content	9.5 - 11.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.