Description

Water-18O is a stable isotopically labeled form of water where the oxygen atom is the non-radioactive isotope Oxygen-18. This product is essential for research and industrial processes requiring precise isotopic labeling as a tracer. It is a critical reagent in metabolic research, environmental studies, and the synthesis of labeled compounds for analytical standards. Industries including pharmaceuticals, academia, and analytical chemistry rely on its high isotopic purity for advanced spectroscopic and mass spectrometric applications.

Application

• Metabolic Pathway Tracing: Used as a tracer in biological and pharmacological research to study metabolic fluxes, drug metabolism, and protein turnover rates.
• NMR Spectroscopy Solvent: Serves as a preferred solvent for 17O-NMR studies and as a deuterium lock solvent in high-field NMR spectrometers.
• Synthesis of Labeled Compounds: A key starting material for the production of Oxygen-18 labeled pharmaceuticals, intermediates, and reference standards.
• Environmental & Hydrological Studies: Employed as a tracer to investigate water cycles, groundwater flow, and atmospheric processes.
• Mass Spectrometry & Analytical Chemistry: Used for internal standardization, calibration, and in isotope dilution mass spectrometry (IDMS) for accurate quantification.
• Chemical Reaction Mechanism Studies: Utilized to elucidate reaction pathways and kinetics in organic and inorganic chemistry.

Basic Information

Product Name	Water-18O
CAS No.	14314-42-2
Molecular Formula	H218O
Molecular Weight	20.02 g/mol
Synonyms	Oxygen-18 Water; H218O; 18O-Labeled Water; Heavy-Oxygen Water; Water (O-18); Deuterium Oxide-18O (when also deuterated); [18O]Water; Isotopic Water (18O)
EINECS	Contact for details

Quality Control

Our Water-18O is produced and handled under strict quality protocols to ensure exceptional isotopic and chemical purity. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (Atom % 18O), chemical purity, and specific conductance. We adhere to cGMP principles where applicable to support its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. To minimize isotopic exchange and maintain label integrity, avoid prolonged exposure to atmospheric moisture and handle under an inert atmosphere when necessary for critical applications.

Specification

Item	Specification
Appearance	Colorless Liquid
Identification (IR)	Conforms
Isotopic Enrichment (Atom % 18O)	≥ 95% (Typical 97-99%)
Chemical Purity (by GC)	≥ 99.9%
Specific Conductance	≤ 5 µS/cm
pH	5.0 - 7.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.