Description

3-Picoline,4-Amino-5-Fluoro-(8Ci) CAS NO 13958-85-5 is a high-purity, fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and fluoro substituents on the picoline backbone, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized nitrogen-containing ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials due to its electron-donating amino group and electron-withdrawing fluoro group.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring new reactions and properties of fluorinated heterocycles.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	3-Picoline,4-Amino-5-Fluoro-(8Ci)
CAS No.	13958-85-5
Molecular Formula	C6H7FN2
Molecular Weight	126.13 g/mol
Synonyms	4-Amino-5-fluoro-3-picoline; 5-Fluoro-4-amino-3-methylpyridine; 3-Methyl-5-fluoro-4-pyridinamine; 4-Amino-5-fluoro-3-methylpyridine; 5-Fluoro-3-methylpyridin-4-amine; 4-Pyridinamine, 5-fluoro-3-methyl-; 3-Picoline, 4-amino-5-fluoro- (8CI)
EINECS	Contact for details

Quality Control

Every batch of 3-Picoline,4-Amino-5-Fluoro-(8Ci) is produced under a strict quality management system. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.