Description

2,6-Difluoroiodobenzene is a high-value halogenated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring iodine and fluorine substituents in the ortho positions, makes it a critical reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom to enhance biological activity and stability.
• Material Science Building Block: Employed in the creation of liquid crystals, organic semiconductors, and advanced polymers where the difluoroiodobenzene moiety imparts specific electronic and physical properties.
• Cross-Coupling Reactions: Serves as an excellent electrophilic partner in palladium-catalyzed reactions such as Suzuki-Miyaura, Stille, and Negishi couplings to form biaryl structures.
• Ligand and Catalyst Development: Utilized for the preparation of specialized ligands and organocatalysts used in asymmetric synthesis.
• Radiolabeling Precursor: Acts as a starting material for the synthesis of radioiodinated compounds used in medical imaging and diagnostics.

Basic Information

Product Name	2,6-Difluoroiodobenzene
CAS No.	13697-89-7
Molecular Formula	C6H3F2I
Molecular Weight	239.99 g/mol
Synonyms	1,3-Difluoro-2-iodobenzene; 2-Iodo-1,3-difluorobenzene; Benzene, 1,3-difluoro-2-iodo-; 2,6-Difluorophenyl iodide; o,o'-Difluoroiodobenzene
EINECS	Contact for details

Quality Control

Our 2,6-Difluoroiodobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.