Description

5-Chloro-2,4-Difluorobenzenesulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites, enabling the efficient introduction of the sulfonyl group and serving as a versatile precursor for more complex sulfonamide and sulfonate structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Material Science: Used in the production of specialty polymers, dyes, and liquid crystal materials.
• Chemical Research: A versatile reagent for constructing complex molecular architectures in medicinal and process chemistry.
• Sulfonamide Library Production: Enables high-throughput parallel synthesis for drug discovery screening programs.

Basic Information

Product Name	5-Chloro-2,4-Difluorobenzenesulfonyl Chloride
CAS No.	13656-57-0
Molecular Formula	C6H2Cl2F2O2S
Molecular Weight	247.04 g/mol
Synonyms	2,4-Difluoro-5-chlorobenzenesulfonyl chloride; 1-Chloro-2,4-difluoro-5-sulfonylchloridebenzene; Benzenesulfonyl chloride, 5-chloro-2,4-difluoro-; 5-Chloro-2,4-difluorophenylsulfonyl chloride; 13656-57-0; 2,4-Difluoro-5-chlorophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2,4-Difluorobenzenesulfonyl Chloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade typically meets a purity specification of ≥97% (by HPLC). Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and a strong acid/organic solvent; keep the container tightly sealed and away from incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.