Description

5-Acetamido-2-Methylbenzenesulphonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its value lies in its role as a versatile electrophilic reagent for introducing the sulfonamide functional group, enabling the creation of molecules with tailored biological and chemical properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drugs, including diuretics, antibacterial agents, and protease inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require the sulfonamide moiety.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing sulfonated dyes and colorants with enhanced solubility and fastness properties.
• Polymer Chemistry: Employed in the modification of polymers and the synthesis of specialty monomers to impart specific functional characteristics.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries for screening.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for the bespoke production of complex organic molecules for clients.

Basic Information

Product Name	5-Acetamido-2-Methylbenzenesulphonyl Chloride
CAS No.	13632-07-0
Molecular Formula	C9H10ClNO3S
Molecular Weight	247.70 g/mol
Synonyms	5-Acetamido-o-toluenesulfonyl chloride; N-[2-Methyl-5-(chlorosulfonyl)phenyl]acetamide; 2-Methyl-5-acetamidobenzenesulfonyl chloride; 5-Acetylamino-2-methylbenzenesulfonyl chloride; Acetamide, N-[2-methyl-5-(chlorosulfonyl)phenyl]-; 5-(Acetylamino)-2-methylbenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Acetamido-2-Methylbenzenesulphonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.