Description

4-Chloro-2-Methyl-1-(Trifluoromethyl)Benzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the combination of chloro, methyl, and trifluoromethyl substituents, which allows for precise structural modifications to tune the properties of target molecules. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules requiring a trifluoromethylphenyl moiety for enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved biological activity and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Specialty Polymer Modifier: Incorporated into polymer chains to impart specific characteristics such as chemical resistance, thermal stability, or altered refractive index.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitutions to construct complex polyfunctional arenes.
• Research & Development: Employed in academic and industrial labs for methodological studies and the discovery of new chemical entities across material science and medicinal chemistry.

Basic Information

Product Name	4-Chloro-2-Methyl-1-(Trifluoromethyl)Benzene
CAS No.	13630-22-3
Molecular Formula	C8H6ClF3
Molecular Weight	194.58 g/mol
Synonyms	2-Methyl-4-chlorobenzotrifluoride; 4-Chloro-α,α,α-trifluoro-o-xylene; 1-Chloro-3-methyl-4-(trifluoromethyl)benzene; 2-Methyl-4-chloro-α,α,α-trifluorotoluene; 4-Chloro-2-methylbenzotrifluoride; 4-Chloro-α,α,α-trifluoro-2-methyltoluene; PCBTF (related acronym); 13630-22-3
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-1-(Trifluoromethyl)Benzene is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for fine chemical synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from strong acids, bases, and oxidizing agents. Due to its highly volatile nature, keep container tightly sealed when not in use. Recommended storage temperature: 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.