Description

4-(Trifluoromethyl)Nicotinonitrile is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a nitrile and a trifluoromethyl group on the pyridine ring, makes it indispensable for introducing fluorine-containing motifs into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug research.
• Agrochemical Synthesis: Used in the design and production of novel herbicides, fungicides, and insecticides with enhanced properties.
• Material Science Precursor: Serves as a starting material for synthesizing specialty polymers, liquid crystals, and electronic chemicals.
• Chemical Research & Development: A versatile reagent for medicinal chemistry and process chemistry in both academic and industrial laboratories.
• Fluorine Chemistry Building Block: Essential for introducing the metabolically stable and lipophilic trifluoromethyl group into complex organic frameworks.

Basic Information

Product Name	4-(Trifluoromethyl)Nicotinonitrile
CAS No.	13600-43-6
Molecular Formula	C7H3F3N2
Molecular Weight	172.11 g/mol
Synonyms	4-(Trifluoromethyl)-3-cyanopyridine; 3-Cyano-4-(trifluoromethyl)pyridine; Nicotinonitrile, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)pyridine-3-carbonitrile; 3-Pyridinecarbonitrile, 4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.