Description

Muscarone is a potent, naturally occurring alkaloid and a key reference standard in neuropharmacological research. Its primary value lies in its role as a selective agonist for muscarinic acetylcholine receptors, making it an indispensable tool for studying cholinergic signaling pathways. This compound is essential for researchers and developers in the pharmaceutical, biotechnology, and academic sectors focused on neuroscience, drug discovery, and toxicology.

Application

• Pharmacological Research: Used as a selective muscarinic acetylcholine receptor (mAChR) agonist to study receptor function, signal transduction, and ligand-receptor interactions.
• Neuroscience & Neuropharmacology: A critical tool for investigating the role of the cholinergic system in cognitive function, memory, and neurodegenerative diseases.
• Drug Discovery & Development: Serves as a reference compound and lead structure for the design and screening of new therapeutics targeting muscarinic receptors.
• Toxicology Studies: Employed in research to understand the mechanisms of action of related toxins and to develop potential antidotes.
• Biochemical Assay Standard: Used to calibrate and validate in vitro and in vivo assays for mAChR activity.
• Academic & Institutional Research: Supports fundamental scientific studies in university and government laboratory settings.

Basic Information

Product Name	Muscarone
CAS No.	13552-60-8
Molecular Formula	C₉H₂₀NO₂⁺
Molecular Weight	174.26 g/mol
Synonyms	Muscarone; L-(+)-Muscarone; (2S,4R,5S)-4-Hydroxy-5-methyl-2-(trimethylammonio)methyl-1,3-dioxolane; Muscarin; Muscarine (related analog); O-Acetylmuscarine (precursor); mAChR Agonist
EINECS	Contact for details

Quality Control

Our Muscarone is produced and handled under strict quality management protocols to ensure the highest standards of purity and consistency for research applications. Each batch is characterized using advanced analytical techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term stability, consider storage at 2-8°C. The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.