Description

Actinonin is a potent and selective small molecule inhibitor of aminopeptidase N (APN/CD13) and matrix metalloproteinases (MMPs), with significant research and therapeutic potential. Its primary value lies in its ability to modulate key biological pathways involved in angiogenesis, tumor growth, and inflammatory processes, making it a critical tool compound for life science research. This high-purity biochemical is essential for pharmaceutical R&D, academic institutions, and biotechnology companies focused on oncology, immunology, and protease inhibitor discovery.

Application

• Biomedical Research: Used as a key pharmacological tool to study the role of aminopeptidase N and matrix metalloproteinases in cancer biology, angiogenesis, and cell invasion.
• Drug Discovery & Development: Serves as a reference compound and lead structure in the development of novel anti-cancer and anti-inflammatory therapeutics targeting metalloproteases.
• Academic & Preclinical Studies: Employed in in vitro and in vivo models to investigate tumor metastasis, wound healing, and inflammatory diseases.
• Enzyme Inhibition Assays: A standard inhibitor for validating assay systems and screening for new inhibitors of APN/CD13 and related metalloproteases.
• Biochemical Mechanism Studies: Utilized to elucidate signaling pathways and cellular processes regulated by metalloprotease activity.

Basic Information

Product Name	Actinonin
CAS No.	13434-13-4
Molecular Formula	C19H33N3O5
Molecular Weight	383.48 g/mol
Synonyms	N-Hydroxy-2-(n-octylamino)hexanohydroxamic Acid; (2R)-2-[(1-Octylamino)ethyl]-N-hydroxybutanediamide; NSC 332003; Antibiotic Actinonin; APN Inhibitor; MMP Inhibitor; CD13 Inhibitor
EINECS	Contact for details

Quality Control

Our Actinonin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity determination by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.