Description

9H-Fluorene-2-Sulfonyl Chloride is a specialized aromatic sulfonyl chloride derivative, serving as a versatile and high-value synthetic building block. Its core value lies in its reactivity as a sulfonylation agent, enabling the introduction of the fluorene-sulfonyl moiety to create novel compounds with tailored properties. This intermediate is critically needed by research and development chemists in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry for creating sulfonamide-based active pharmaceutical ingredients (APIs).
• Organic Synthesis Reagent: Used as a sulfonylation agent in organic reactions to introduce the 9H-fluorene-2-sulfonyl protecting group or functional handle onto amines, alcohols, and other nucleophiles.
• Material Science Research: Employed in the development of novel organic electronic materials, such as semiconductors or light-emitting compounds, where the fluorene core contributes to charge transport and luminescent properties.
• Agrochemical Synthesis: Intermediate in the research and development of new agrochemicals, including herbicides and fungicides, leveraging its bioactive sulfonyl chloride functionality.
• Dye and Pigment Chemistry: Serves as a precursor for synthesizing specialized dyes and fluorescent markers due to the inherent photophysical characteristics of the fluorene structure.
• Cross-coupling Reactions: Potential substrate in metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing complex biaryl systems after appropriate functional group transformation.

Basic Information

Product Name	9H-Fluorene-2-Sulfonyl Chloride
CAS No.	13354-17-1
Molecular Formula	C₁₃H₉ClO₂S
Molecular Weight	264.72 g/mol
Synonyms	2-Fluorenesulfonyl Chloride; 9H-Fluorene-2-sulphonyl chloride; Fluorene-2-sulfonyl Chloride; 2-(Chlorosulfonyl)fluorene; 9H-Fluoren-2-ylsulfonyl Chloride; NSC 403107; 2-Fluorenylsulfonyl Chloride
EINECS	Contact for details

Quality Control

Our 9H-Fluorene-2-Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.