Description

4-Acetamido-2,5-Dimethoxybenzenesulphonyl Chloride is a specialized aromatic sulphonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its dual functionality as both a sulfonylating agent and a protected aniline, enabling the construction of complex sulfonamide and sulfonate structures. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including potential diuretics, antibiotics, and carbonic anhydrase inhibitors.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with sulfonylurea or sulfonamide moieties.
• Dye and Pigment Manufacturing: Used in the production of specialized azo dyes and sulfonated colorants.
• Polymer Chemistry: Monomer or modifier for introducing sulfonyl groups into polymers to alter solubility or reactivity.
• Chemical Research & Development: Versatile reagent for exploring new synthetic pathways and creating compound libraries for high-throughput screening.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing client-specific fine chemicals.

Basic Information

Product Name	4-Acetamido-2,5-Dimethoxybenzenesulphonyl Chloride
CAS No.	13279-58-8
Molecular Formula	C10H12ClNO5S
Molecular Weight	293.72 g/mol
Synonyms	N-[2,5-Dimethoxy-4-(sulfonylchloride)phenyl]acetamide; 4-Acetamido-2,5-dimethoxybenzenesulfonyl chloride; 2,5-Dimethoxy-4-acetamidobenzenesulfonyl chloride; 4-Acetylamino-2,5-dimethoxybenzenesulfonyl chloride; Acetamide, N-[2,5-dimethoxy-4-(sulfonylchloride)phenyl]-; 4-(Acetylamino)-2,5-dimethoxybenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Acetamido-2,5-Dimethoxybenzenesulphonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.