Description

3-Bromophenyl Chlorothioformate is a specialized organosulfur reagent featuring both a reactive chlorothioformate group and a bromophenyl moiety. This compound is valued for its dual functionality, serving as a versatile building block in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing sulfur-containing scaffolds and as an intermediate in heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing thioester or thiocarbonate functionalities.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the bromophenyl group imparts specific biological activity.
• Polymer Chemistry: Acts as a monomer or chain-transfer agent in the development of specialty polymers with unique thermal or chemical resistance properties.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing sulfur-based ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in surface modification and the creation of advanced organic materials with tailored properties.
• Chemical Biology Probes: Useful for bioconjugation and labeling strategies due to its electrophilic chloroformate group.

Basic Information

Product Name	3-Bromophenyl Chlorothioformate
CAS No.	13222-74-7
Molecular Formula	C7H4BrClOS
Molecular Weight	251.53 g/mol
Synonyms	3-Bromophenyl Chlorothioformate; Chlorothioformic Acid O-(3-Bromophenyl) Ester; 3-Bromophenyl Chlorocarbonothioate; 3-Bromophenyl Chlorosulfenylformate; m-Bromophenyl Chlorothioformate; (3-Bromophenyloxy)carbonothioic Chloride; Carbonochloridothioic Acid O-(3-Bromophenyl) Ester
EINECS	Contact for details

Quality Control

Our 3-Bromophenyl Chlorothioformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents. Use appropriate containment to prevent moisture ingress and minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.