Description

4-Fluoro-2-Iodotoluene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both fluorine and iodine substituents on a toluene backbone, makes it a critical intermediate for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly through Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging the reactivity of the iodine moiety for structural diversification.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating fluorinated and iodinated aromatic cores in electronic and display materials.
• Organic Ligand Preparation: Employed in the synthesis of specialized ligands for catalysis and coordination chemistry.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial labs.
• Fluorine Chemistry Studies: Used as a model compound to study the electronic effects and reactivity of fluoro- and iodo-arenes.

Basic Information

Item	Detail
Product Name	4-Fluoro-2-Iodotoluene
CAS No.	13194-67-7
Molecular Formula	C7H6FI
Molecular Weight	236.03 g/mol
Synonyms	2-Iodo-4-fluorotoluene; 1-Fluoro-4-methyl-2-iodobenzene; 4-Fluoro-2-iodo-1-methylbenzene; 2-Iodo-4-methylfluorobenzene; 4-Methyl-2-iodofluorobenzene; 4-Fluoro-o-iodotoluene; Toluene, 4-fluoro-2-iodo-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Iodotoluene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to consistent quality and supply chain reliability supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent contamination and moisture ingress.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.