Description

Thiochrome Diphosphate is a specialized biochemical derivative of thiamine (vitamin B1) that serves as a critical analytical standard and reagent. Its primary value lies in its high specificity for the quantitative determination of thiamine and its phosphate esters via fluorometric methods. This compound is essential for quality control laboratories, research institutions, and manufacturers in the pharmaceutical, nutraceutical, and food & beverage industries who require precise vitamin analysis to ensure product efficacy and regulatory compliance.

Application

• Fluorometric Assay Standard: Primary use as a reference standard for the precise quantification of thiamine (Vitamin B1) and its phosphorylated derivatives (thiamine monophosphate, thiamine diphosphate) in various matrices.
• Pharmaceutical Quality Control: Critical for assay and purity testing of thiamine-containing pharmaceutical formulations, including tablets, injections, and multivitamin complexes.
• Food & Beverage Fortification Analysis: Used to verify and monitor thiamine levels in fortified foods, infant formula, cereals, and beverages to meet nutritional labeling claims.
• Clinical & Diagnostic Research: Employed in research settings to study thiamine metabolism, deficiency disorders, and to develop diagnostic assays for conditions like beriberi and Wernicke-Korsakoff syndrome.
• Nutraceutical & Dietary Supplement Testing: Ensures the potency and label accuracy of vitamin B1 in dietary supplements and functional food products.
• Biochemical Research: Serves as a key reagent and intermediate in enzymatic studies and metabolic pathway research related to coenzyme function.

Basic Information

Product Name	Thiochrome Diphosphate
CAS No.	13185-55-2
Molecular Formula	C₁₂H₁₅N₄O₇P₂S⁺
Molecular Weight	421.27 g/mol
Synonyms	Thiochrome Diphosphate; Thiochrome Pyrophosphate; Thiamine Pyrophosphate Thiochrome; Thiochrome TPP; Thiochrome-Cocarboxylase; 7,8-Dimethyl-10-[(2-methyl-4-amino-5-pyrimidinyl)methyl]isoalloxazine-5'-diphosphate; Thiochrome Derivative of Thiamine Diphosphate
EINECS	Contact for details

Quality Control

Our Thiochrome Diphosphate is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for analytical applications. Each lot is subjected to comprehensive testing, including identity confirmation by spectroscopic methods, purity assessment by HPLC, and verification of suitability as a fluorometric standard. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Fluorescence Suitability	Suitable for use as a fluorometric standard
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.