Description

Z-Gly-Gly-Phe-Oh is a protected tripeptide derivative, widely utilized as a key building block in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is primarily needed by the pharmaceutical, biotechnology, and academic research sectors for applications in drug discovery, proteomics, and the development of therapeutic peptides.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of longer, biologically active peptide chains in drug development.
• Solid-Phase Peptide Synthesis (SPPS): Used as a protected fragment to extend peptide chains on resin, ensuring correct sequence assembly.
• Biochemical Research: Serves as a standard or substrate in enzymatic studies and proteomics research.
• Therapeutic Peptide Production: A key raw material in the manufacture of peptide-based APIs for various therapeutic areas.
• Custom Peptide Synthesis: Employed by CROs and CDMOs for the contract manufacturing of specific peptide sequences for clients.

Basic Information

Product Name	Z-Gly-Gly-Phe-Oh
CAS No.	13171-93-2
Molecular Formula	C₂₁H₂₃N₃O₆
Molecular Weight	413.43 g/mol
Synonyms	Z-Gly-Gly-L-Phenylalanine; N-Carbobenzoxy-glycyl-glycyl-L-phenylalanine; Benzyloxycarbonyl-Gly-Gly-Phe-OH; CBZ-Gly-Gly-Phe-OH; Nα-(Benzyloxycarbonyl)glycylglycyl-L-phenylalanine; Z-GGF-OH; (2S)-2-[[2-[(2-[[(Benzyloxy)carbonyl]amino]acetyl)amino]acetyl]amino]-3-phenylpropanoic acid; CBZ-Gly-Gly-L-Phe-OH
EINECS	Contact for details

Quality Control

Our Z-Gly-Gly-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatograms are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	-15° to -20° (c=1 in DMF)
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.