Description

Anhydrotetrodotoxin is a potent neurotoxin and a derivative of tetrodotoxin, a compound famously associated with pufferfish. This high-purity chemical is critical for advanced neuroscience research and pharmacological studies, particularly in the investigation of voltage-gated sodium channels. It serves as an essential tool for researchers and pharmaceutical developers in the life sciences, toxicology, and drug discovery sectors who require precise, reliable reference standards for their work.

Application

• Neuroscience Research: As a selective sodium channel blocker, it is used to study neuronal signaling, action potentials, and nerve cell physiology.
• Pharmacological Tool Compound: Employed in high-throughput screening and target validation assays for drug discovery programs focused on pain management and neurological disorders.
• Toxicology & Safety Testing: Acts as a critical reference standard in analytical methods for detecting and quantifying tetrodotoxin and its analogs in food and environmental safety testing.
• Biochemical Reagent: Used in the development of sensitive detection kits and biosensors for marine biotoxins.
• Academic & Institutional Research: Provides a key reagent for university and government labs studying ion channel function and marine toxin mechanisms of action.

Basic Information

Product Name	Anhydrotetrodotoxin
CAS No.	13072-89-4
Molecular Formula	C₁₁H₁₇N₃O₈
Molecular Weight	319.27 g/mol
Synonyms	4,9-Anhydrotetrodotoxin; 4,9-AnhydroTTX; Tetrodotoxin 4,9-hemilactal; 4-epitetrodotoxin; TTX analog; DeoxyTetrodotoxin (related derivative); Marine neurotoxin derivative
EINECS	Contact for details

Quality Control

Our Anhydrotetrodotoxin is produced under stringent quality management systems to ensure the highest standards of purity and consistency for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for reference standard materials to guarantee reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.