Description

3β-[(3-o-Methyl-2,6-Dideoxy-β-D-Lyxo-Hexopyranosyl)Oxy]-14-Hydroxy-5β,14β-Carda-20(22)-Enolide is a high-purity cardiac glycoside derivative, a class of compounds known for their potent and specific biological activity. This compound matters as a critical reference standard and advanced pharmaceutical intermediate for research and development in cardiovascular therapeutics. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) focused on novel cardiology treatments.

Application

• Pharmaceutical Reference Standard: Used for qualitative and quantitative analysis in method development, validation, and quality control of cardiac drug products.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthetic pathways for novel cardioactive drugs.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate the mechanisms of cardiac glycosides on sodium-potassium ATPase pumps.
• Preclinical Development: Utilized in pharmacological and toxicological profiling of new chemical entities targeting heart failure and arrhythmias.
• Analytical Chemistry: Acts as a critical calibrant and system suitability compound in High-Performance Liquid Chromatography (HPLC) and Liquid Chromatography-Mass Spectrometry (LC-MS) applications.

Basic Information

Product Name	3β-[(3-o-Methyl-2,6-Dideoxy-β-D-Lyxo-Hexopyranosyl)Oxy]-14-Hydroxy-5β,14β-Carda-20(22)-Enolide
CAS No.	12738-19-1
Molecular Formula	C30H44O9
Molecular Weight	548.67 g/mol
Synonyms	Digitoxigenin 3-O-methyl-2,6-dideoxy-β-D-lyxo-hexopyranoside; 3β-[(3-O-Methyl-2,6-dideoxy-β-D-lyxo-hexopyranosyl)oxy]-14-hydroxy-5β,14β-card-20(22)-enolide; 3-O-Methyl-2,6-dideoxy-β-D-lyxo-hexopyranosyl digitoxigenin; 3-O-Methyldigitoxigenin lyxoside; CAS 12738-19-1; A cardiac glycoside aglycone derivative; 3-O-Methyl-digitoxigenin β-D-lyxoside
EINECS	Contact for details

Quality Control

Our 3β-[(3-o-Methyl-2,6-Dideoxy-β-D-Lyxo-Hexopyranosyl)Oxy]-14-Hydroxy-5β,14β-Carda-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation via IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.