Description

Sodiummercaptododecaborate,Bsh,10Benriched CAS NO 12448-24-7 is a boron-10 enriched sodium salt of mercaptododecaborate, a key compound in Boron Neutron Capture Therapy (BNCT). This product matters for its critical role in providing a high concentration of the 10B isotope, which is essential for effective tumor targeting and neutron capture in advanced cancer treatments. It is primarily needed by pharmaceutical research institutions, radiopharmaceutical manufacturers, and clinical facilities developing and administering BNCT.

Application

• Boron Neutron Capture Therapy (BNCT): As a primary or intermediate compound in the synthesis of tumor-targeting boron delivery agents for experimental and clinical cancer treatment.
• Radiopharmaceutical Development: Serving as a precursor for the synthesis of novel boronated compounds used in diagnostic and therapeutic radiopharmaceuticals.
• Nuclear Medicine Research: Utilized in preclinical studies to evaluate the biodistribution, pharmacokinetics, and efficacy of boron-based drugs.
• Isotope-Labeled Compound Synthesis: Acting as a source of enriched 10B for creating labeled molecules for research in chemistry and biology.
• Neutron Detection and Shielding: Potential use in the fabrication of materials for neutron detection devices or shielding applications due to the high neutron capture cross-section of 10B.

Basic Information

Product Name	Sodiummercaptododecaborate,Bsh,10Benriched
CAS No.	12448-24-7
Molecular Formula	NaB12H11SH
Molecular Weight	~210.32 g/mol (for 11B form, enriched form varies)
Synonyms	Sodium Mercaptoundecahydrododecaborate; Sodium Borocaptate; BSH; Na2B12H11SH; Disodium undecahydro-12-mercaptododecaborate; Sulfhydryl boron hydride sodium salt; Boron-10 enriched BSH; BNCT agent BSH; Sodium dodecaboranyl mercaptide
EINECS	Contact for details

Quality Control

Our Sodiummercaptododecaborate,Bsh,10Benriched is manufactured under strict controls to ensure the high purity and isotopic enrichment required for research and pharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as Boron-10 isotopic enrichment, chemical purity, and impurity profiles. We adhere to relevant Good Manufacturing Practice (GMP) guidelines for active pharmaceutical ingredients (APIs) where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., argon or nitrogen) in a desiccator to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Assay (Titration)	≥ 95.0%
Boron-10 Isotopic Enrichment	> 95 atom % 10B
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.