Description

Antimycin is a potent, naturally occurring antibiotic complex produced by *Streptomyces* bacteria, primarily known for its role as a specific inhibitor of mitochondrial electron transport. This compound is a critical research tool in biochemistry and cell biology for studying cellular respiration, apoptosis, and energy metabolism. It is essential for researchers in pharmaceutical development, agricultural sciences studying fungicides, and academic institutions investigating mitochondrial function and programmed cell death pathways.

Application

• Biochemical Research: A standard inhibitor used to study mitochondrial complex III (cytochrome bc1 complex) in oxidative phosphorylation and electron transport chain mechanisms.
• Apoptosis Induction: Used in cell biology laboratories to induce apoptosis (programmed cell death) in various cell lines by disrupting mitochondrial membrane potential.
• Agricultural Research: Serves as a model compound and active ingredient in research for developing novel fungicidal and pesticidal agents.
• Pharmaceutical Screening: Employed in drug discovery programs as a reference standard for identifying and validating new compounds targeting mitochondrial function.
• Metabolic Studies: Utilized in metabolic research to investigate ATP production, reactive oxygen species (ROS) generation, and bioenergetics.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or biological assay calibration.

Basic Information

Item	Detail
Product Name	Antimycin
CAS No.	11118-72-2
Molecular Formula	C28H40N2O9
Molecular Weight	548.63 g/mol
Synonyms	Antimycin A; Antimycin A1; Antipiricullin; Blastmycin; Virosin; NSC 13387; UNII-642LT6G8L9; 3-[(2R,3S,6S,7R,8R)-3-[(2S,3S)-3-Formamido-2-hydroxybutanoyl]oxy-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl]amino-3-oxopropanoic acid
EINECS	Contact for details

Quality Control

Our Antimycin is produced and handled under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is easily oxidized; for long-term storage, consider under an inert atmosphere. Keep container tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0% (Antimycin A complex)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 1.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.