Description

Venturicidin is a potent, macrocyclic lactone antibiotic and ATP synthase inhibitor derived from *Streptomyces* species. Its primary value lies in its specific and high-affinity inhibition of mitochondrial and chloroplast ATP synthase, making it an indispensable research tool in biochemistry and cell biology. This compound is essential for scientists and manufacturers in the pharmaceutical research, agrochemical development, and life science reagent sectors studying oxidative phosphorylation, bioenergetics, and metabolic pathways.

Application

• Biochemical Research: A critical tool for studying the mechanism, kinetics, and structure of F0F1-ATP synthase in mitochondria and chloroplasts.
• Cell Biology & Physiology: Used to investigate cellular energy metabolism, oxidative stress, and apoptosis by selectively inhibiting mitochondrial ATP production.
• Agrochemical Mode-of-Action Studies: Employed as a reference compound in the research and development of novel fungicides and herbicides that target energy metabolism.
• Pharmaceutical Discovery: Serves as a molecular probe in drug discovery programs targeting metabolic diseases and disorders linked to mitochondrial dysfunction.
• Academic & Industrial R&D: A standard reagent in laboratories focused on bioenergetics, plant physiology, and microbial biochemistry.

Basic Information

Product Name	Venturicidin
CAS No.	11021-88-8
Molecular Formula	C48H76O12
Molecular Weight	845.1 g/mol
Synonyms	Venturicidin A; Antibiotic 63-90; Antibiotic X-63; NSC 163500; Venturicidin complex; Venturicidin mixture; 3,9-Dihydroxy-4,8,10,12-tetramethyl-6-[(1E)-1-methyl-2-oxo-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyethylidene]-11-propan-2-yl-1-oxacyclododecane-2,5,7,13-tetrone
EINECS	Contact for details

Quality Control

Our Venturicidin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and microbiological potency assessment. A detailed Certificate of Analysis (COA) documenting identity, purity, and assay results is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Assay (Potency)	≥ 90.0% (Microbiological)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.