Description

3-Bromo-4'-Fluorobiphenyl is a high-purity halogenated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which provides two distinct reactive sites for selective functionalization, enabling the construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorinated biphenyl core for enhanced biological activity and stability.
• Liquid Crystal & OLED Materials: Acts as a fundamental building block for creating specialized organic semiconductors and liquid crystal molecules used in display technologies.
• Cross-Coupling Reactions: A versatile substrate in Suzuki, Stille, and Negishi cross-coupling reactions to form complex biaryl systems prevalent in many functional materials.
• Organic Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Research & Development: Serves as a standard reagent in academic and industrial R&D labs for method development and exploring new chemical spaces.

Basic Information

Product Name	3-Bromo-4'-Fluorobiphenyl
CAS No.	10540-35-9
Molecular Formula	C12H8BrF
Molecular Weight	251.10 g/mol
Synonyms	4'-Fluoro-3-bromobiphenyl; 3-Bromo-4-fluorobiphenyl; [1,1'-Biphenyl]-3-bromo-4'-fluoro; 3-Brom-4'-fluor-biphenyl; Biphenyl, 3-bromo-4'-fluoro-; 4-Fluorophenyl-3-bromobenzene
EINECS	Contact for details

Quality Control

Our 3-Bromo-4'-Fluorobiphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.