Description

2-Methyl-2-Propanesulfonyl Chloride is a versatile sulfonyl chloride derivative, a key building block in organic synthesis. Its primary value lies in its role as a robust sulfonylation reagent, enabling the introduction of the tert-butylsulfonyl group to create compounds with enhanced stability and specific steric properties. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), advanced intermediates, and functional materials.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of sulfonamide-based drugs and APIs, where it acts as a sulfonylating agent.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that incorporate sulfonyl functional groups for enhanced activity.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce sulfonyl chloride groups into polymer chains for specialty materials.
• Peptide Modification: Useful in bioconjugation and peptide chemistry for labeling or protecting specific amino acid residues.
• Organic Synthesis Reagent: Serves as a versatile building block for constructing complex organic molecules in research and development laboratories.
• Dye and Pigment Manufacturing: Utilized in the synthesis of sulfonated dyes and colorants.

Basic Information

Product Name	2-Methyl-2-Propanesulfonyl Chloride
CAS No.	10490-22-9
Molecular Formula	C₄H₉ClO₂S
Molecular Weight	156.63 g/mol
Synonyms	tert-Butylsulfonyl chloride; 2-Methyl-2-propanesulfonyl chloride; tert-Butanesulfonyl chloride; t-Butylsulfonyl chloride; 2-Propanesulfonyl chloride, 2-methyl-; NSC 163044; (CH3)3CSO2Cl
EINECS	234-001-9

Quality Control

Our 2-Methyl-2-Propanesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods, to ensure high purity and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, assay, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is kept tightly sealed to exclude moisture and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.