Description

4-Methyl-1-Naphthalenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, introducing the 4-methylnaphthalene-1-sulfonyl moiety to create compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing sulfonamide-based drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require specific sulfonamide functionalities.
• Dye and Pigment Manufacturing: Acts as a precursor for creating sulfonated dyes and pigments with enhanced solubility and color fastness.
• Polymer Chemistry: Employed in the modification of polymers to introduce sulfonyl groups, altering physical properties like thermal stability and solubility.
• Chemical Research & Development: A valuable reagent in organic synthesis labs for constructing complex molecular architectures and exploring new reaction pathways.
• Material Science: Used in the synthesis of specialty chemicals and advanced materials, such as liquid crystals and organic semiconductors.

Basic Information

Product Name	4-Methyl-1-Naphthalenesulfonyl Chloride
CAS No.	10447-11-7
Molecular Formula	C₁₁H₉ClO₂S
Molecular Weight	240.70 g/mol
Synonyms	1-Naphthalenesulfonyl chloride, 4-methyl-; 4-Methylnaphthalene-1-sulfonyl chloride; p-Tolyl-1-naphthalenesulfonyl chloride; 1-Sulfo-4-methylnaphthalene chloride; 4-Methyl-1-naphthylsulfonyl chloride; MNSC; 4-Methyl-1-naphthalenesulphonyl chloride
EINECS	233-949-5

Quality Control

Our 4-Methyl-1-Naphthalenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.