Description

(2R,3R,4R,5R)-2-Acetamido-3,4,5-Trihydroxy-1-Oxo-6-Sulfooxy-Hexane is a high-purity, stereochemically defined monosaccharide derivative of significant interest in advanced biochemical research and synthesis. This compound serves as a critical building block and reference standard for the development of glycosylated molecules and enzyme substrates. It is primarily utilized by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, glycobiology, and the synthesis of complex bioactive molecules.

Application

• Biochemical Research: Acts as a key intermediate and reference standard in carbohydrate and glycoconjugate synthesis.
• Enzyme Substrate Studies: Used to investigate the activity and specificity of sulfotransferases and other glycosylation-related enzymes.
• Pharmaceutical Development: Serves as a chiral building block for the synthesis of novel drug candidates, particularly in antiviral and anti-inflammatory research.
• Glycobiology: Essential for studying cell signaling, recognition processes, and the structure-function relationships of complex carbohydrates.
• Analytical Standard: Employed as a high-purity standard for HPLC, LC-MS, and NMR analysis in quality control and method development.

Basic Information

Product Name	(2R,3R,4R,5R)-2-Acetamido-3,4,5-Trihydroxy-1-Oxo-6-Sulfooxy-Hexane
CAS No.	10357-00-3
Molecular Formula	C8H15NO10S
Molecular Weight	317.27 g/mol
Synonyms	N-Acetyl-D-glucosamine 6-sulfate; D-Glucosamine, N-acetyl-, 6-(hydrogen sulfate); 2-Acetamido-2-deoxy-D-glucopyranose 6-sulfate; 6-O-Sulfo-N-acetyl-D-glucosamine; GlcNAc-6-S; NAcGlc-6-S; N-Acetylglucosamine-6-sulfate; AGlcNS
EINECS	Contact for details

Quality Control

Our (2R,3R,4R,5R)-2-Acetamido-3,4,5-Trihydroxy-1-Oxo-6-Sulfooxy-Hexane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific optical rotation verification to ensure stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.