Description

1-(Phenylsulphonyl)Aziridine (CAS NO 10302-15-5) is a specialized sulfonylated aziridine derivative, a versatile building block in advanced organic synthesis. Its value lies in its strained three-membered aziridine ring, which acts as a highly reactive electrophile for ring-opening reactions, enabling the efficient introduction of functionalized amine motifs. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries who require precise molecular construction for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key synthon for constructing complex nitrogen-containing heterocycles and bioactive molecules, including potential kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific amine functionalities.
• Polymer Modification: Serves as a cross-linking agent or monomer for producing specialty polymers with tailored properties, such as epoxy resins and polyamines.
• Bioconjugation Chemistry: Utilized for labeling and modifying biomolecules (proteins, peptides) due to its selective reactivity with nucleophilic sites.
• Material Science Research: Employed in the synthesis of advanced materials, including dendrimers, supramolecular assemblies, and surface coatings.
• Ligand and Catalyst Development: Acts as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1-(Phenylsulphonyl)Aziridine
CAS No.	10302-15-5
Molecular Formula	C8H9NO2S
Molecular Weight	183.23 g/mol
Synonyms	N-(Phenylsulfonyl)aziridine; 1-(Benzenesulfonyl)aziridine; Aziridine, 1-(phenylsulfonyl)-; N-Phenylsulfonylaziridine; 1-Phenylsulfonylaziridine; 2-(Phenylsulfonyl)aziridine (tautomer); Benzenesulfonyl aziridine
EINECS	233-672-6

Quality Control

Our 1-(Phenylsulphonyl)Aziridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure compliance with exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and moisture. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.