Description

3-Methoxybenzenesulfonyl Chloride is a versatile arylsulfonyl chloride derivative, a key building block in organic synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the 3-methoxybenzenesulfonyl moiety to create sulfonamides, sulfonate esters, and other functionalized compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require the sulfonyl chloride functional group.
• Dyestuff and Pigment Manufacturing: Serves as an intermediate for creating sulfonated dyes and colorants with enhanced properties.
• Polymer Chemistry: Employed in the modification of polymers and the synthesis of specialty monomers containing sulfonate groups.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry for constructing complex molecular architectures.
• Ligand and Catalyst Preparation: Used to synthesize sulfonamide ligands for metal complexes in catalytic applications.

Basic Information

Product Name	3-Methoxybenzenesulfonyl Chloride
CAS No.	10130-74-2
Molecular Formula	C7H7ClO3S
Molecular Weight	206.65 g/mol
Synonyms	m-Methoxybenzenesulfonyl Chloride; 3-Methoxybenzene-1-sulfonyl Chloride; m-Anisylsulfonyl Chloride; 3-Methoxyphenylsulfonyl Chloride; 1-Methoxy-3-(chlorosulfonyl)benzene; NSC 403119; Benzenesulfonyl chloride, 3-methoxy-
EINECS	233-357-3

Quality Control

Our 3-Methoxybenzenesulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed to exclude moisture and stored separately from bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline mass
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.