Description

4-Amino-3-Chlorobenzenesulfonyl Fluoride is a high-purity, versatile sulfonyl fluoride derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino group and a reactive sulfonyl fluoride moiety, makes it an essential precursor for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and pesticides with enhanced efficacy.
• Chemical Biology & Proteomics: Used as a reactive handle in activity-based protein profiling (ABPP) and covalent inhibitor design due to the sulfonyl fluoride group's selectivity.
• Material Science: Intermediate for synthesizing specialty polymers, dyes, and functional materials requiring sulfonamide linkages.
• Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and synthetic methodology development.

Basic Information

Product Name	4-Amino-3-Chlorobenzenesulfonyl Fluoride
CAS No.	1996-51-6
Molecular Formula	C6H5ClFNO2S
Molecular Weight	209.63 g/mol
Synonyms	3-Chloro-4-aminobenzenesulfonyl Fluoride; 4-Amino-3-chlorobenzene-1-sulfonyl Fluoride; Benzenesulfonyl fluoride, 4-amino-3-chloro-; 3-Chloro-4-aminophenylsulfonyl Fluoride; 4-Amino-3-chlorophenylsulfonyl Fluoride; 3-Chloro-4-aminobenzenesulfonfluoride; 4-Amino-3-chlorobenzenesulfonfluoride
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chlorobenzenesulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.